Jiaogulan (Gynostemma pentaphyllum)
Rich in gypenosides, Jiaogulan has been reported to modulate AMPK signaling, reduce
oxidative stress, and influence lipid metabolism. Preclinical findings suggest
cytoprotective and anti-proliferative effects in multiple cellular models.
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Himalayan Goji (Lycium barbarum)
Contains Lycium barbarum polysaccharides associated with immunomodulatory activity,
including effects on cytokine expression and macrophage activation. Antioxidant and
potential anti-tumor mechanisms have been observed in vitro and in vivo.
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Açaí (Euterpe oleracea)
High in anthocyanins and polyphenols, Açaí demonstrates strong antioxidant capacity.
Experimental studies suggest potential roles in ROS scavenging, modulation of inflammatory
mediators, and inhibition of tumor cell proliferation.
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Peruvian Maca (Lepidium meyenii)
Bioactive macamides and macaenes have been associated with mitochondrial support,
endocrine modulation, and neuroprotective effects. Experimental data suggest influence on
energy metabolism and cellular stress response pathways.
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American Ginseng (Panax quinquefolius)
Contains ginsenosides with documented effects on immune modulation, glucose metabolism,
and anti-inflammatory signaling. Evidence also suggests potential roles in fatigue
reduction and adjunctive support.
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Schisandra chinensis
Lignans including schisandrin have been studied for hepatoprotective, antioxidant, and
pro-apoptotic activity. Mechanistic studies demonstrate activation of JNK/p38 MAPK
pathways and ROS-mediated mitochondrial apoptosis in cancer cell lines.
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Glycyrrhiza uralensis
Licochalcone A and related flavonoids have demonstrated anti-inflammatory, antioxidant,
and anti-proliferative effects. Reported mechanisms include NF-κB inhibition and
apoptosis induction in tumor models.
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Rhodiola rosea
Phenylpropanoids such as salidroside contribute to adaptogenic effects, including
modulation of HPA axis activity, reduction of oxidative stress, and potential anti-fatigue
and neuroprotective outcomes.
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Astragalus Root (Astragalus membranaceus)
Polysaccharides and saponins are associated with immunomodulatory activity, including
T-cell activation and cytokine regulation. Frequently studied as an adjunct in oncology
settings for immune support.
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Reishi Mushroom (Ganoderma lucidum)
Contains β-glucans and triterpenes with documented immunomodulatory and anti-tumor
properties. Reported mechanisms include NK cell activation, cytokine modulation, and
apoptosis induction.
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Catuaba (Erythroxylum catuaba)
Traditionally used for CNS support; emerging data suggest potential neuroprotective and
antioxidant activity, though clinical evidence remains limited.
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Guarana (Paullinia cupana)
Contains caffeine, catechins, and tannins. Demonstrates antioxidant activity and may
influence cellular metabolism and fatigue-related pathways.
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Ashwagandha (Withania somnifera)
Withanolides have been studied for anti-inflammatory, immunomodulatory, and anti-cancer
properties, including apoptosis induction and tumor growth inhibition in preclinical models.
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Purple Lapacho (Tabebuia impetiginosa)
Contains naphthoquinones including lapachol and β-lapachone, which have been studied for
cytotoxic and anti-proliferative effects in cancer-related models.
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Polysaccharopeptides from Coriolus versicolor
PSP and related fractions are documented for immune modulation, particularly in oncology
adjunct settings, including enhancement of host immune response signaling.
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Baicalin
A flavone glycoside derived from Scutellaria baicalensis, exhibiting
anti-inflammatory, antioxidant, and anti-tumor effects through multiple signaling pathways,
including PI3K/Akt and MAPK.
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Noto Ginseng (Panax notoginseng)
Rich in notoginsenosides; associated with anti-inflammatory, anti-angiogenic, and
anti-proliferative effects in preclinical oncology models.
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Fo-Ti (Polygonum multiflorum / He Shou Wu)
Contains stilbene glycosides and anthraquinones. Investigated for antioxidant, anti-aging,
and potential cytoprotective effects; hepatotoxicity considerations are noted in the literature.
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Modified Citrus Pectin
Low molecular weight pectin shown to bind galectin-3, a protein implicated in tumor
progression, metastasis, and fibrosis in mechanistic studies.
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Black Ginger (Kaempferia parviflora)
Methoxyflavones have been studied for potential effects on mitochondrial function, energy
metabolism, and vascular performance.
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Maral Root (Rhaponticum carthamoides)
Contains ecdysteroids associated with anabolic and adaptogenic effects, with reported
influence on protein synthesis and recovery-related pathways.
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Grade A Maple Syrup
Contains polyphenolic compounds with antioxidant activity and may contribute to overall
redox balance within the formulation matrix.
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Shilajit
A mineral-rich exudate containing fulvic acid and dibenzo-α-pyrones. Studied for
mitochondrial support, electron transport chain activity, and antioxidant effects.
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